On 13 September, France reported its first case of indigenous Dengue. Five days later, it confirmed a second; both cases are in Nice. Another 6 or 7 cases are under investigation. Although the French territories of Mayotte, Guadeloupe, and Martinique have had major dengue outbreaks since August, metropolitan France is not a country where Dengue normally occurs (see HealthMap’s Dengue Map collaboration with CDC to see which parts of the world are high-risk). Four departments in southern France have a mosquito capable of carrying Dengue. France has begun aggressive spraying efforts to prevent Dengue from becoming established in the area, an unlikely even according to officials.